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Issue 3, 2018
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Food Function

Impact of dietary supplementation with olive and thyme phenols on alpha-tocopherol concentration in the muscle and liver of adult Wistar rats

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* Corresponding authors

Food Technology Department, UTPV-XaRTA, Agrotecnio Research Center, Escola Tècnica Superior d'Enginyeria Agrària, University of Lleida, Avda. Alcalde Rovira Roure 191, 25198 Lleida, Spain motilva@tecal.udl.es +34 973 702596 +34 973 702817

Estudis de Ciències de la Salut, Universitat Oberta de Catalunya, Barcelona, Spain

A preliminary study to evaluate the effect of dietary supplementation with olive phenols (oleuropein, hydroxytyrosol and secoiridoids), thyme phenols and a combination of these (5 mg per kg rat weight per day) on the α-tocopherol concentrations in the muscle and liver of healthy adult Wistar rats over 21 days was conducted. In addition, the excretion of α-tocopherol through the faeces was examined. The results demonstrated that the diet supplemented with some phenolic compounds of olive and thyme increased α-tocopherol ( < 0.05) in the liver of female rats, although the α-tocopherol content in the diet of all groups was identical. In addition, a synergic effect between the olive phenols and thyme was observed. Therefore, our study indicates a protective effect of olive and thyme phenols supplemented in the diet on α-tocopherol, resulting in a higher concentration of endogenous α-tocopherol in the rat liver.

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Publication details

The article was received on 02 Oct 2017, accepted on 20 Jan 2018 and first published on 22 Jan 2018

Article type: Paper
DOI: 10.1039/C7FO01533J
Citation: , 2018, 9 , 1433-1443
Food Funct.

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Further reading and references

; Faculty of Sexual and Reproductive Healthcare (December 2014)

; NICE Clinical Guideline (September 2014)

; NICE CKS, December 2017 (UK access only)

; Faculty of Sexual and Reproductive Healthcare, 2016

; Faculty of Sexual Reproductive Healthcare (September 2015)

; Progestin-only contraceptives: effects on weight. Cochrane Database Syst Rev. 2016 Aug 28(8):CD008815. doi: 10.1002/14651858.CD008815.pub4.

; Contraceptive failure in the United States, Contraception, 2011

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