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Food Function

Impact of dietary supplementation with olive and thyme phenols on alpha-tocopherol concentration in the muscle and liver of adult Wistar rats

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Maria-José Motilva *

* Corresponding authors

Food Technology Department, UTPV-XaRTA, Agrotecnio Research Center, Escola Tècnica Superior d'Enginyeria Agrària, University of Lleida, Avda. Alcalde Rovira Roure 191, 25198 Lleida, Spain +34 973 702596 +34 973 702817

Estudis de Ciències de la Salut, Universitat Oberta de Catalunya, Barcelona, Spain

A preliminary study to evaluate the effect of dietary supplementation with olive phenols (oleuropein, hydroxytyrosol and secoiridoids), thyme phenols and a combination of these (5 mg per kg rat weight per day) on the α-tocopherol concentrations in the muscle and liver of healthy adult Wistar rats over 21 days was conducted. In addition, the excretion of α-tocopherol through the faeces was examined. The results demonstrated that the diet supplemented with some phenolic compounds of olive and thyme increased α-tocopherol ( < 0.05) in the liver of female rats, although the α-tocopherol content in the diet of all groups was identical. In addition, a synergic effect between the olive phenols and thyme was observed. Therefore, our study indicates a protective effect of olive and thyme phenols supplemented in the diet on α-tocopherol, resulting in a higher concentration of endogenous α-tocopherol in the rat liver.

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Publication details

The article was received on 02 Oct 2017, accepted on 20 Jan 2018 and first published on 22 Jan 2018

Article type: Paper
DOI: 10.1039/C7FO01533J
Citation: , 2018, 9 , 1433-1443
Food Funct.

The injection is given into a muscle, usually in the buttock, or into the thigh or tummy (abdomen). It should not be given during pregnancy. It is therefore important to be sure you are not pregnant when you have your first injection. However, if you were already pregnant without knowing, there is no evidence that it does the baby or the pregnancy any harm.

Sayana Press® has been designed so that you can give it to yourself. This may be useful if you have trouble getting to your surgery or clinic. Your doctor or nurse can teach you how to do this safely.

The doctor or nurse will tell you which type of injection you have and how long it is until the next injection. It can be given up to two weeks early. This may be convenient if, for example, you are due to be on a holiday when your next injection is due.

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Contraceptive Implant

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Further reading and references

; Faculty of Sexual and Reproductive Healthcare (December 2014)

; NICE Clinical Guideline (September 2014)

; NICE CKS, December 2017 (UK access only)

; Faculty of Sexual and Reproductive Healthcare, 2016

; Faculty of Sexual Reproductive Healthcare (September 2015)

; Progestin-only contraceptives: effects on weight. Cochrane Database Syst Rev. 2016 Aug 28(8):CD008815. doi: 10.1002/14651858.CD008815.pub4.

; Contraceptive failure in the United States, Contraception, 2011

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